See the main signs Fatigue is one of the main symptoms of the new variant of coronavirus - Omicron. This is explained by the president of the South African Medical Association, Angelique Cutzi, writes Sky News. According to her, patients who tested positive for the new COVID complained of sore throats, mild headaches and body aches. So far, those infected have not reported a loss of smell. There is no decrease in the level of oxygen in the blood.